There are currently 2 approved vaccines: Pfizer vaccine is 2 shots given 21 days apart, while Moderna vaccine is 2 shots given 28 days apart. A couple of other vaccines are nearing the end of their studies and should be seeking FDA approval soon. Most likely, you will not have a choice of which to pick. Fortunately, we feel the current options are too similar to differentiate.
Yes. Although the technique to produce these vaccines is new to us, it has been studied for over a decade. Before FDA approval, it has been studied in thousands of patients. Now with release, they have been given to millions, including all 4 of the doctors at WSCA. Although there is a genetic component, it does NOT get into your cell nucleus and cannot alter your DNA. With millions of doses given, the side effects have all been typical of every other vaccine.
Yes. It is safe for you. NONE of the vaccines under development or currently available in the United States are live virus vaccines. This is purposeful so that everyone can get them. The vaccines are currently messenger RNA based, which is the recipe our bodies use to make proteins. This recipe includes what is needed to stimulate your immune system to react against the virus if you get the infection. COVID-19 is a new virus. Without the vaccine, no one will have natural immunity. So, this is the ONLY additional way to protect yourself from getting the infection, which can be serious and life threatening. We are concerned that having an autoimmune condition may increase the risk of serious consequences from the virus. It is not clear if your medications increase this risk. There is some evidence that some biologics may PREVENT serious disease. Stay tuned.
These vaccines appear to be >95% effective over the time studied-which is several months already. You most likely will need a booster even after the 1st 2 doses. We should learn when this is needed by following the thousands of people already in the studies that have at least a 3-4 month “head start”. It most likely will be at least yearly, like the flu vaccine. Good immunity against the virus occurs a week or 2 AFTER the second dose, so we will all need to continue to practice distancing and wear masks. There appear to be some strains that have mutated to a more virulent strain, mostly in Europe. Considering the immunology of the vaccine, it most likely will cover these strains although we need to follow closely. Vaccines can adapt to these strains as well.
If you already had COVID, we believe you should be vaccinated also. But we do not have information on this situation either. People with prior infection were excluded from the vaccine study. There have been reports of some patients losing that immunity 3 months after contracting the virus.
-Based on recommendations for flu vaccines, we are now recommending a 2 week hold of methotrexate after receiving your vaccine. You will want to hold for 2 weeks after each shot if your arthritis is stable. This will enhance your body’s ability to develop immunity.
-We also think that vaccination should NOT be given within 3 months if you are receiving Rituxan infusions. This will maximize response of the vaccine. Also avoid the vaccine in the month BEFORE you get your Rituxan.
-Ideally, we would like to have your prednisone dose below 10 mg prior to vaccination if this is possible.
The CDC is recommending that patients with chronic conditions are vaccinated in Group 1C. Group 1A is frontline healthcare providers and long-term care residents. Group 1B includes front line workers like police, firemen and teachers. Next will be people over age 75, who are at higher risk for more serious infections. As this rolls out, it will become evident when you should get the vaccine. We anticipate expanding locations to get the vaccine such as pharmacies and grocery stores so that long lines are avoided. Stay in touch. Feel free to contact us for advice or if there’s confusion.
We do not know how long you will be protected from the vaccine. The current studies only guarantee a few months. However, the study will continue for 2 years to document how long patients remain protected. We will know this answer over time.
-In the published Pfizer study, the main observed side effects were fatigue, headaches, muscle aches, arm pain, joint pain, fevers, chills, vomiting and diarrhea. All resolved within 2 days and they were more common after the second vaccine dose. Remember that side effects are not reported in most people; they are possibilities and not guarantees.
-There have been a few cases of severe allergic reactions. No one has died from these allergic reactions because the vaccine is given in a hospital setting. This reaction has only happened in less than 10 people and has changed the recommended monitoring period after the vaccine is given to 30 minutes to monitor for these side effects. (expect to sit somewhere to watch for allergic reactions for 30 minutes until we learn more).
The infection fatality rate for people with COVID symptoms ranges between 0.5-3.6% in studies, while there are no fatalities (deaths) reported in vaccine recipients. Obviously, we believe these small, short lived risks are far outweighed by the benefit!